Keep track of for symptoms and indications of withdrawal; whenever they come about, elevate the dose to the preceding degree and taper more slowly but surely.
Swallow complete or open up the capsule and sprinkle contents onto delicate food stuff or into a cup, administer straight into mouth and swallow right away; rinse mouth to make sure all capsule contents are actually swallowed.
Impairment of Fertility Scientific studies in animals To guage the probable affect of oxycodone on fertility haven't been executed.
The concomitant possibility of anticholinergic prescription drugs could end in improved hazard of urinary retention and/or significant constipation, which can cause paralytic ileus.
Keep in mind, retain this and all other medicines out of your get to of youngsters, never ever share your medicines with Other individuals, and use oxycodone only for the sign prescribed.
The specific mechanism on the analgesic motion is not known. On the other hand, unique CNS opioid receptors for endogenous compounds with opioid-like exercise are discovered through the brain and spinal wire and therefore are believed to Engage in a role during the analgesic consequences of the drug.
Tell your Health care supplier If you're: Expecting or planning to grow to be pregnant. Prolonged usage of oxycodone HCl tablets through pregnancy may cause withdrawal symptoms as part of your new child little one that may be daily life-threatening Otherwise identified and dealt with.
If a CNS depressant or benzodiazepine are desired in the affected individual by now on an opioid analgesic: Initiate using a lower Original dose from the benzodiazepine or other CNS depressant; titrate based upon clinical response.
one)]. Instruct individuals to not share oxycodone HCl with Other people and also to get methods to guard oxycodone HCl from theft and misuse.
Never ever crush or break an oxycodone pill to inhale the powder or blend it into a liquid to inject the drug into your vein. This may cause death.
For those who pass up a dose, get your upcoming dose at check here your standard time. Oxycontin needs to be taken one pill at a time. Will not pre-soak, lick, or wet the tablet just before inserting it in the mouth to stay away from choking on the tablet.
Oxycodone may make you drowsy and gradual your reflexes. Avoid driving or pursuits demanding alertness till you understand how oxycodone impacts you.
Oxycodone is a complete opioid agonist and is relatively selective for the mu-opioid receptor, even though it can bind to other opioid receptors at bigger doses. The principal therapeutic motion of oxycodone is analgesia.
Keep an eye on for respiratory melancholy, In particular in the course of initiation and adhering to any rise in dose; close monitoring will likely be necessary in sufferers at greater risk and/or These obtaining concomitant medications that boost the risk of respiratory depression.